Generation and characterization of highly active intermediates by hypervalent halogen and xenon compounds

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K15097
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Chemical pharmacy
• Research Institution: The University of Tokyo
• Principal Investigator: Miyamoto Kazunori 東京大学, 大学院薬学系研究科(薬学部), 講師 (40403696)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: 超原子価 / ヨウ素 / 臭素 / 二原子炭素 / キセノン / 脱離能

Outline of Final Research Achievements

We successfully generated several super-reactive intermediates such as diatomic carbon, meta-benzene, bis(triflyl)carbene under mild reaction conditions in a flask and discovered their unique physical/chemical characters. The vastly enhanced nucleofugality of hypervalent halogen and xenon leaving groups are responsible for the generation of highly reactive intermediates.

Free Research Field

有機典型元素化学