2016 Fiscal Year Final Research Report
Development of magnetic antibiotics
| Project/Area Number |
16K15205
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
General pharmacology
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| Research Institution | Yokohama City University |
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Principal Investigator |
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| Project Period (FY) |
2016-04-01 – 2017-03-31
|
| Keywords | 抗生剤 / 磁性 / ドラッグデリバリー |
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| Outline of Final Research Achievements |
The method for evaluating metal material has been applied to pharmaceutical compounds. Accordingly, we have found compounds with strong magnetism, which also has toxicity. With chemical researchers, we have synthesized magnetic compounds with less toxicity. In this research project, we have examined this compound and studied its application for magnetizing antibiotic compounds. We have synthesized ampicillin which has been magnetized by this compounds. We have found that this magnetized ampicillin was indeed weakly magnetic. Our findings suggest that it is feasible to magnetize antibiotics. In the future study it will be needed to evaluate antibiotic activity of magnetized ampicillin and its guided delivery by magnet.
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| Free Research Field |
生理学
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