2017 Fiscal Year Final Research Report
Single cell analysis of T lymphocytes in the intestinal immune system
| Project/Area Number |
16K15294
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Immunology
|
|---|
| Research Institution | Keio University |
|---|
Principal Investigator |
HASE Koji 慶應義塾大学, 薬学部(芝共立), 教授 (20359714)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
城口 克之 国立研究開発法人理化学研究所, 生命システム研究センター, ユニットリーダー (00454059)
|
|---|
| Project Period (FY) |
2016-04-01 – 2018-03-31
|
| Keywords | 大腸炎 / シングルセル解析 |
|---|
| Outline of Final Research Achievements |
Conventional methods such as flow cytometry and quantitative PCR have limitation to analyze individual lymphocyte cells. Here we established single cell analysis method by taking advantage of DNA barcoding, and analyzed TCR repertoire in the gut of experimental colitis model.
|
| Free Research Field |
免疫学
|
