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2018 Fiscal Year Final Research Report

Attitudes towards and acceptance of HPV vaccine in Japanese mothers of adolescents living in the UK and Australia

Research Project

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Project/Area Number 16K15367
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Hygiene and public health
Research InstitutionHokkaido University

Principal Investigator

Hanley Sharon  北海道大学, 医学研究院, 特任講師 (80529412)

Research Collaborator Simms Kate  
Project Period (FY) 2016-04-01 – 2019-03-31
KeywordsHPV vaccine / vaccine hesitancy / cervical cancer / Policy1-Cervix model / impact analysis
Outline of Final Research Achievements

HPV vaccine confidence decreased in Japan after unfounded reports on vaccine safety appeared in the media. This study aimed to evaluate HPV vaccine acceptance in Japanese parents of adolescent girls living in the UK and Australia. A secondary aim was to quantify the impact of suspension of proactive recommendations for the HPV vaccine in Japan to date.
The most important factor for deciding whether to vaccinate a daughter against HPV was the opinion of the mother, regardless of whether the father had a bio/medical background or not.
Regarding the impact of suspension of proactive recommendations for the HPV vaccine, we found around 55,800-63,700 preventable cases and 9,300-10,800 preventable deaths from cervical cancer will occur over the next 50 years compared to if uptake has remained high. However, swift recovery of uptake in 2020 resulting in 70% coverage for 12yr old girls and 50% uptake in catch-up cohorts aged 13-20yrs with HPV9 could prevent around 80% of these deaths.

Free Research Field

Cancer epidemiology, public health

Academic Significance and Societal Importance of the Research Achievements

The results suggest interventions focusing on mothers are important to help increase HPV vaccine confidence and acceptability. The impact analysis shows that swift restoration of coverage, including catch-up vaccination, could mitigate most of the damage caused by suspension of recommendations.

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Published: 2020-03-30   Modified: 2020-07-01  

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