2017 Fiscal Year Final Research Report
Establishment of innovative culture system, kidney-on-chip, utilizing microdevice
| Project/Area Number |
16K15464
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Kidney internal medicine
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
藤井 輝夫 東京大学, 生産技術研究所, 教授 (30251474)
稲城 玲子 東京大学, 医学部附属病院, 特任准教授 (50232509)
田中 哲洋 東京大学, 医学部附属病院, 講師 (90508079)
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| Research Collaborator |
DOI Kotaro 東京大学, 大学院医学系研究科, 大学院生
CHIKAMORI Masatomo 東京大学, 大学院医学系研究科, 大学院生
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | マイクロデバイス / organ on chip / 医工連携 / podocyte / 尿細管 |
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| Outline of Final Research Achievements |
We established an innovative culture system with microdevice, kidney-on-chip, which reproduces physical stress of glomerular filtrates and in vivo conditions. We established polydimethylsiloxane (PDMS)-based compartment microfluidic cocultivation system of podocytes and renal tubular cells on multi-pore membrane coated with extracellular matrix.
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| Free Research Field |
腎臓内科学
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