Omic analysis from single cell circulating tumor cells of oral cancer

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K15833
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Surgical dentistry
• Research Institution: National Cancer Center Japan
• Principal Investigator: Kazufumi Honda 国立研究開発法人国立がん研究センター, 研究所, ユニット長 (10260936)
• Co-Investigator(Kenkyū-buntansha): 森 泰昌 国立研究開発法人国立がん研究センター, 中央病院, 医員 (00296708) ; 吉本 世一 国立研究開発法人国立がん研究センター, 中央病院, 科長 (00462242)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: 末梢循環腫瘍細胞 / 1細胞解析 / オミクス解析

Outline of Final Research Achievements

Liquid biopsy has recently gained attention as a real-time monitoring method for patients with cancer. Circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) released into the bloodstream from both the primary tumor and metastases may reflect current tumor status.　Although it is considering that CTCs are consisting the heterogeneous of population, the biological behavior of single cell CTC has not identified yet. To identify behavior of single cell CTC, we developed the omics analysis of single cell CTC.

Free Research Field

オミクス解析