2017 Fiscal Year Final Research Report
Development of bioactive PEEK that spontaneously bond to living bone
| Project/Area Number |
16K16401
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | PEEK / 繊維強化PEEK / アパタイト核 / アパタイト形成能 |
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| Outline of Final Research Achievements |
By sulfuric acid treatment, mesh-like pores were formed on the surfaces of PEEK and fiber-reinforced PEEK. Then, bioactive PEEK and bioactive fiber reinforced PEEK were obtained by subsequent glow-discharge treatment and apatite nuclei treatment. It was found that the untreated substrate and acid-treated one showed hydrophobicity, whereas the glow-discharge-treated substrate and subsequently apatite nuclei-treated one showed hydrophilicity. After sulfuric acid treatment, formation of sulfo groups was shown. After the subsequent glow-discharge treatment, increase of sulfo groups and formation of carboxyl groups were shown. When the bioactive substrates were immersed in SBF, it was found that the entire surfaces were covered with apatite layer within 1 day and high apatite-forming ability was achieved.
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| Free Research Field |
無機材料化学・生体材料学
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