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2018 Fiscal Year Final Research Report

Development of rehabilitation technique to induce inhibitory neural activity in patients with focal hand dystonia

Research Project

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Project/Area Number 16K16433
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionIbaraki Prefectural University of Health Science

Principal Investigator

Aoyama Toshiyuki  茨城県立医療大学, 保健医療学部, 助教 (30516571)

Research Collaborator KOHNO Yutaka  
TOMITA Kazuhide  
KANEKO Fuminari  
Project Period (FY) 2016-04-01 – 2019-03-31
Keywords抑制性神経活動 / フォーカルハンドジストニア / 経頭蓋磁気刺激 / F波
Outline of Final Research Achievements

Focal hand dystonia is a disabling movement disorder that often occurs in musicians who use hand repeatedly and effective rehabilitation has not yet been established. Some previous studies revealed that this symptom is associated with impaired inhibitory neural activity. Therefore, we examined neurophysiological changes induced by motor imagery to verify whether motor imagery is effective as a treatment to promote inhibitory neural activity. As a result, we found inhibitory effects on the neural activity of the antagonist muscle during motor imagery. These results suggest that the possibility of motor imagery for the treatment of focal hand dystonia. In the future, we have to verify the effect of motor imagery therapy on the focal hand dystonia patients.

Free Research Field

神経科学

Academic Significance and Societal Importance of the Research Achievements

本研究は,運動を脳内でイメージすることで,脳の抑制性の神経活動が促されることを示した初めての研究である。神経疾患の中には,フォーカルハンドジストニアだけでなく,脳卒中の痙縮など,抑制性の神経活動に問題が生じた結果として生じる障害が存在する。本研究成果は,そのような障害に対する新しいリハビリテーション手法として運動イメージ想起という方法が有用な可能性を示しており,今後の臨床研究成果が期待される。

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Published: 2020-03-30  

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