Association of physical inactivity with decline in physical function and functional status in hemodialysis patients

2019 Fiscal Year Final Research Report

• Project/Area Number: 16K16466
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Hyogo University of Health Sciences (2019); Kitasato University (2016-2018)
• Principal Investigator: Matsuzawa Ryota 兵庫医療大学, リハビリテーション学部, 講師 (20770184)
• Project Period (FY): 2016-04-01 – 2020-03-31
• Keywords: 身体活動 / リハビリテーション / 透析 / 腎不全 / フレイル / サルコペニア / 運動療法 / 理学療法

Outline of Final Research Achievements

Although the clinical importance of physical activity for patients on hemodialysis has already been emphasized in clinical practice guidelines published by academic society of the US and Europe, there is less recognition of it in the clinical care for Japanese patients. The main goals of this study were (1) to examine the association of a change in the functional status over a 1-year period with all-cause mortality, (2) to detect the minimum recommendation of habitual physical activity, and (3) to investigate the relationship between physical activity and decline in physical function and functional status of the dialysis populations. As a result, we showed the importance of physical activity in order to prevent the decline in physical function and functional status, and decrease mortality risk.

Free Research Field

リハビリテーション

Academic Significance and Societal Importance of the Research Achievements

本研究は、透析患者の日常生活活動および身体活動量に焦点を当てて疫学調査を行い、その実態や生命予後との関連について検証した。各国の診療ガイドラインで強調されているにも関わらず、血液透析患者の日常生活活動レベルを維持・向上するための医学的管理は、未だ透析医療のルーチンケアには含まれていない。本研究は透析患者における身体活動量の臨床的意義を改めて見出し、日常生活活動レベルを維持・向上させるための医学的管理法の確立に貢献することができたと思われる。