Synthesis of sequence-regurated polymers from bio-renewable compounds

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K17912
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Polymer chemistry
• Research Institution: Gunma University (2017); Kanazawa University (2016)
• Principal Investigator: Ryohei Kakuchi 群馬大学, 大学院理工学府, 助教 (00743816)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: 多成分連結反応 / 高分子反応

Outline of Final Research Achievements

In this work, the multi-component reactions (MCRs) were utilized for polymer synthesis in order to synthesize sequence-controlled polymers. For this, isocyanide-based MCRs such as the Passerini and the Ugi reactions were conducted with amino acid derived monomers, which enabled at least their oligomeriations. In addition, lignin-derived chemicals, such as vanillin and syringaldehyde, were successfully combined with MCR-based polymer synthesis. As a result, the successful Kabachnik-Fields three component reaction of the polymers featuring vanillin and syringaldehyde proceeded with a practically perfect consumption of the starting aldehydes, essentially affording polymeric α-amino phosphonates. These results should pave the way toward sequence-regulated constructions of polymers starting from bio-renewable compounds.

Free Research Field

高分子化学