2017 Fiscal Year Final Research Report
Development of cascade solid catalyst by immobilization of enzymes into protein crystals
| Project/Area Number |
16K17931
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Bio-related chemistry
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
ABE Satoshi 東京工業大学, 生命理工学院, 助教 (40508595)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | 多角体 / 酵素 |
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| Outline of Final Research Achievements |
In this research, we have synthesized polyhedra mutant, which have a large pore in unit cell by deletion of amino acid residues. We found that positively charged SfGFP is largely encapsulated into Polyhedra crystals than negatively charged SfGFP. We have prepared polyhedra crystal including Lipase enzyme. In future, we will synthesize polyhedra crystals including two enzymes, lipase and alcohol dehydrogenase and investigate the cascade reaction.
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| Free Research Field |
生体関連化学
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