2017 Fiscal Year Final Research Report
Development of new method for screening anticancer drugs that target topoisomerases by using DNA origami
| Project/Area Number |
16K17934
|
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Bio-related chemistry
|
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| Research Institution | Kyoto University |
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Principal Investigator |
|
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| Project Period (FY) |
2016-04-01 – 2018-03-31
|
| Keywords | DNA origami / Inhibitors / Topoisomerase / HS-AFM / Drug screening / Single-molecule analysis / Rotaxane / Catenane |
|---|
| Outline of Final Research Achievements |
The supramolecular assemblies of the topologically interlocked components inside a DNA origami were constructed. Such assemblies of the functional structures are promising in the fields of molecular switches, motors, sensors, and logic devices.
|
| Free Research Field |
DNA nanotechnology
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