2017 Fiscal Year Final Research Report
Microbiome analysis and the relation with epigenome abnormality and immune response using U.S. and Japanese gastrointestinal cancers
| Project/Area Number |
16K18423
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Tumor biology
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
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| Research Collaborator |
Nosho Katsuhiko 札幌医科大学, 医学部, 講師 (10597339)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | microbiome / Fusobacterium / 膵癌 |
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| Outline of Final Research Achievements |
Fusobacterium species were detected in pancreatic cancer tissue. Although no significant association was found between Fusobacterium species and molecular alterations of pancreatic cancers, the tumor Fusobacterium species status was independently associated with shorter survival of pancreatic cancer. Thus, our data suggest that tumor Fusobacterium species is a promising biomarker of pancreatic cancer and could open up exciting opportunities to improve our understanding of the pathogenesis of this fatal disease.
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| Free Research Field |
消化器癌
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