2018 Fiscal Year Final Research Report
A genomic investigation into the adaptive diversity of a wild Arabidopsis species
| Project/Area Number |
16K18623
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ecology/Environment
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Kubota Shosei 東京大学, 大学院総合文化研究科, 助教 (10771701)
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| Project Period (FY) |
2016-04-01 – 2019-03-31
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| Keywords | 次世代シーケンサー / ゲノムワイドSNP解析 / 適応遺伝子 / 生態ニッチモデル |
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| Outline of Final Research Achievements |
Here, we collected Arabidopsis halleri subsp. gemmifera individuals from more than 100 populations throughout its distribution in Japan. Next generation sequencing was applied to each individual to obtain a genome wide SNP (single nucleotide polymorphism) dataset. Candidate genes underlying environmental adaptation were detected from a genome-wide association study (GWAS) between SNPs and environmental components obtained from a 1 km mesh GIS dataset. Ecological niche modeling based on these adaptive genes revealed that response to simulated global warming can differ between the opposing alleles. These results highlight the genetic mechanisms underlying intra specific adaptive variation.
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| Free Research Field |
ゲノム生態学
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| Academic Significance and Societal Importance of the Research Achievements |
様々な中立的遺伝マーカーの発達により、ひとつの野生生物種に内包される多様性の理解は大きく進んだ。一方で、中立的遺伝マーカーが示す“多様性”は、種内の分集団がたどってきた歴史を反映するものであり、種が内包する適応力の多様性（高温耐性，乾燥耐性などが分集団間で異なること）を必ずしも反映するものではない。今後は地球規模での気候変動が予想されているが、そうした環境変化に野生生物がどのように応答するかを予測する上で、適応力の種内多様性を遺伝子レベルで把握することは非常に重要と言える。
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