2017 Fiscal Year Final Research Report
Does the distribution of muscle mass increase the risk of fracture independently of total muscle mass? A large scale cohort study of Japanese women
| Project/Area Number |
16K19263
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Kindai University |
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Principal Investigator |
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | 筋量分布 / 骨折リスク / 地域在住女性 / コホート研究 |
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| Outline of Final Research Achievements |
We examined whether the distribution of muscle mass increases the risk of fracture independently of total muscle mass in community-dwelling women. Five hundred seventy women were analyzed. The distribution of muscle mass was used as a predictor, and the incident vertebral fractures were used as an outcome. The lower limb muscle mass/total muscle mass ratio was significantly associated with incident vertebral fractures independently of total muscle mass (odds ratio 0.697 for 1SD decrease, 95%CI 0.500-0.970). Other muscle mass distribution index showed no significant association with incident vertebral fractures. The findings from the present study suggest that distribution of muscle mass is associated with fracture risk independently of total muscle mass.
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| Free Research Field |
予防医学
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