Construction of influenza diagnostic scoring system and recommendation of proper use of rapid influenza diagnostic test

2019 Fiscal Year Final Research Report

• Project/Area Number: 16K19322
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: General internal medicine(including psychosomatic medicine)
• Research Institution: Juntendo University
• Principal Investigator: Tanei Mika 順天堂大学, 医学部, 非常勤助教 (60749597)
• Project Period (FY): 2016-04-01 – 2020-03-31
• Keywords: インフルエンザウイルス / 感染症 / 総合診療 / 臨床研究 / 診断特性

Outline of Final Research Achievements

Rapid influenza diagnostic tests(RIDTs), which are often uesed in clinical situation, have high specificity and low sensitivity. We did not detect more specific symptom of influenza than other febrile respiratory diseases. We could not construct a diagnostic scoring system for influenza. However, clinician's diagnostic accuracy, its sensitivity is 93.3% and the soecificity is 60%. During flu season, clinicians can diagnose influenza accurately. When doctors suspect the patients have influenza, they should refrain from using RIDTs.

Free Research Field

総合診療

Academic Significance and Societal Importance of the Research Achievements

診療で汎用されるインフルエンザ迅速診断キットは特異度は高いが感度は低い。インフルエンザの症状に特異的な症状は他の発熱性呼吸器疾患と比較し特になく、インフルエンザ診断スコアリングシステム構築は困難であったが、医師の診断特性は感度93.3％、特異度60%であり、流行状態、病歴、接触歴、身体所見から臨床診断が可能である。医師がインフルエンザを強く疑う時はキットの使用を控えることで無駄な検査を削減できる。