2017 Fiscal Year Final Research Report
Role of adiponectin in the pathogenesis of pulmonary fibrosis
| Project/Area Number |
16K19451
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | アディポネクチン / 肺線維症 / 肺気腫 |
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| Outline of Final Research Achievements |
Idiopathic pulmonary fibrosis (IPF) is a fatal age-associated disease that is characterized by progressive and irreversible scarring of the lung. However, the pathogenesis of IPF is not completely understood and current therapies are limited to those that reduce the rate of functional decline in patients with mild-to-moderate disease. Accumulating evidence suggests adiponectin (APN) may be a promising therapy against fibrotic diseases. Here, we determine whether APN protects against pulmonary fibrosis in bleomycin-induced mice
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| Free Research Field |
呼吸器内科
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