2017 Fiscal Year Final Research Report
The contribution of a novel epithelial-derived cytokine to the host defense against pneumococcal pneumonia
| Project/Area Number |
16K19466
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Keio University |
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Principal Investigator |
Kamata Hirofumi 慶應義塾大学, 医学部(信濃町), 助教 (60528545)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | 肺炎球菌肺炎 / Sectm1a |
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| Outline of Final Research Achievements |
We purchased Sectm1a KO sperm from University California, Davis（UC Davis）and created Sectm1a hetero KO mice in RIKEN TSUKUBA Campus followed by crossing them in our faclity. We succeeded in breeding Sectm1a KO mice stably in our facility. To the best of our knowledge, there has been no report in which Sectm1a KO mice were used and thus our preset study could provide novel insights to further elucidate the mechanisms through which host immune sytem works during pneuococcal pneumonia.
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| Free Research Field |
呼吸器感染症
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