2017 Fiscal Year Final Research Report
The association between serum macro TSH Level and sleep disorder
| Project/Area Number |
16K19562
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Endocrinology
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| Research Institution | Hyogo Medical University |
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Principal Investigator |
Kadoya Manabu 兵庫医科大学, 医学部, 助教 (90755109)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | マクロTSH / 睡眠障害 |
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| Outline of Final Research Achievements |
We investigated structural differences between serum macro TSH and free TSH and the association of macro TSH with sleep quality in humans. In results, increase in serum macro TSH levels is associated with low sleep quality and is regulated in a distinct fashion from free TSH potentially due to an altered glycosylation structure. We showed the possibility that macro TSH was a marker of sleep dysorder.
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| Free Research Field |
内分泌代謝
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