Pathophysiological analysis of airway and obstructive diseases using 4D-dynamic ventilation CT

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K19837
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: University of the Ryukyus
• Principal Investigator: Yamashiro Tsuneo 琉球大学, 医学(系)研究科(研究院), 講師 (30772545)
• Research Collaborator: MORIYA Hiroshi 大原綜合病院, 副院長 ; TSUKAGOSHI Shinsuke キャノンメディカルシステムズ株式会社, CT開発部, 主任 ; KIMOTO Tatsuya キャノンメディカルシステムズ株式会社, ヘルスケアICT開発センター, 主任
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: CT / 慢性閉塞性肺疾患 / 中枢気道 / 呼吸運動

Outline of Final Research Achievements

Various pathophysiological findings were newly observed in COPD patients by the 4D-dynamic ventilation CT, which were summarized and published as multiple papers by international medical journals. They include 'paradoxical' respiratory movements of the proxial airways, asynchrony between lobar movements, and strange compression of the heart during expiration in COPD patients. I strongly believe that these new observations in COPD patients will make an influence on the future therapeutic strategies for COPD.

Free Research Field

放射線医学