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2017 Fiscal Year Final Research Report

Development of new MR lymphangiography by using Gd(III)-DTPA-Nanodiamond Particles

Research Project

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Project/Area Number 16K19861
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionTokai University

Principal Investigator

MATSUMOTO Tomohiro  東海大学, 医学部, 講師 (30710983)

Project Period (FY) 2016-04-01 – 2018-03-31
Keywordsナノダイヤモンド / MRI / リンパ管造影 / MRリンパ管造影
Outline of Final Research Achievements

Lymphangiography was successfully performed in rabbits. Three-dimensional maximum intensity projection (3-D MIP) image on post-lymphangiographic multidetector CT in anteroposterior view clearly shows the lymphatic system in rabbits. Lymphangiography is feasible and the visibility of the lymphatic system on post-lymphangiographic MDCT in a rabbit model provides enough information for interventional radiologists to perform preclinical lymphatic interventions.
We found that Gd(III)-DTPA-nanodiamond (Gd-DTPA-Nd) particles formed persistent agglomerates in animal magnetic resonance imaging study. We must resolve the problem of persistent agglomerates to use Gd-DTPA-Nd particles in daily clinical works.

Free Research Field

放射線医学

URL: 

Published: 2019-03-29  

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