Development of a novel surgical marking method using low power laser light.

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K19986
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Respiratory surgery
• Research Institution: Tokyo Medical University
• Principal Investigator: OHTANI KEISHI 東京医科大学, 医学部, 客員講師 (70384956)
• Research Collaborator: IKEDA Norihiko 東京医科大学, 医学部, 教授 ; ARAI Tsunenori 慶應義塾大学, 理工学部物理情報工学科, 教授 ; MATSUBAYASHI Jun 東京医科大学, 医学部, 准教授 ; SACHIO Maehara 東京医科大学, 医学部, 助教 ; IMAI Kentaro 東京医科大学, 医学部, 助教 ; KUDO Yujin 東京医科大学, 医学部, 助教 ; ONO Syotaro 東京医科大学, 医学部, 助教 ; NAGASE Kumiko 東京医科大学, 医学部, 研究助手
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: 肺癌 / 小型肺癌 / レーザー / 術中マーキング

Outline of Final Research Achievements

Small lung nodules in peripheral lung are difficult to identify during surgery. Therefore, we developed a new safe and reliable intraoperative marking method using a low power laser light. It irradiated close to the lesion from a bronchus, the site of the lesion can be identified from the lung surface.
We conducted an animal experiment and were able to observe the laser light irradiated in bronchus from the lung surface until the depth of 2cm from pleura. We also could observe the laser light until the depth of 1cm from pleura in human resected lung. Any damages were not detected in the lung around the laser irradiated area in pathological findings.
It might be possible to confirm the localization of small nodules in peripheral lung safely using low power laser light during surgery.

Free Research Field

呼吸器外科