development of human cultured lumh node

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K20362
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Plastic surgery
• Research Institution: University of the Ryukyus
• Principal Investigator: Yamazaki Shun 琉球大学, 医学部附属病院, 特命助教 (60464856)
• Research Collaborator: SUNAMI HIROSHI 琉球大学, 医学部, 特命助教 (50374723)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: リンパ節 / 人工リンパ節 / 培養 / ヒトリンパ節

Outline of Final Research Achievements

We successfully cultured human lymph node cells. A portion of a lymph node without metastasis among the neck lymph nodes dissected in head and neck cancer patients was collected and cultured for a maximum of 18 days. When　the lymph node tissue was pulverized, washed and cultured, the cells of the lymph node, the blood cells and the interstitial cells,were cultured.
In this study, human lymph nodes cells were proved to be relatively easily cultured. Further research will show the possibility of growing lymph nodes from own node cells without using stem cells such as iPS cells.

Free Research Field

形成外科