Challenge to the expansion of the adaptation cases with the implant treatment by Chemical Treatment Process by using calcium phosphate slurry that we originally developed

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K20529
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: Hokkaido University
• Principal Investigator: Ito Tatsuro 北海道大学, 大学病院, 医員 (70750933)
• Research Collaborator: YOKOYAMA ATSURO 北海道大学, 大学院歯学研究科, 教授 (20210627) ; TAKADA SARI 北海道大学, 大学院歯学研究科, 大学院生 ; MAEDA YUKARI 北海道大学, 大学院歯学研究科, 大学院生
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: スラリー埋没加熱処理法 / インプラント / ハイドロキシアパタイト / 糖尿病

Outline of Final Research Achievements

In this study, I diagnosed screws made by titanium as an implant body and put processing to attach hydroxyapatite (ingredient same as a bone) to the these screws surface called Chemical treatment process by using calcium phosphate slurry. I implanted the surface treated screw and not treated screw in the rat jaw bone which suffered from diabetes inherently, and observed the newly formed bone around the implanted screws.
As a result, at 1 week after surgery, newly bone was observed around both types of screws. Although, more close adherence to adjoining osteocyte was occurred around surface treated screw than not treated. At 4 weeks, close adherence to adjoining osteocyte was observed around both of screws, but newly bone around surface treated screw was bonding to existing jaw bone more closely and newly bone around not treated peeled off the existing bone. So it was suggested that the Chemical treatment process was effective for osseointegration on the bone that contracts a diabates.

Free Research Field

生体材料