Making of a neurodifferentiation amnion sheet of dental pulp cell aiming at treatment of the dental pulp disease

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K20542
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: Kyoto Prefectural University of Medicine
• Principal Investigator: honjo kenichi 京都府立医科大学, 医学(系)研究科(研究院), 特任助教 (00756877)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: 歯髄由来細胞 / 羊膜 / 培養細胞シート / 神経分化誘導

Outline of Final Research Achievements

Making of a neurodifferentiation amnion sheet of dental pulp cell and aiming for the development of the new treatment for dental pulp disease. I cultured dental pulp cell on the amnion and differentiated to nerve it. I transplanted a culture sheet to the molar tooth of approximately 20 weeks of age Fischer 344 nude rats (male). Approximately four weeks later, performing examination of the histologic immunohistology, accepted the local existence of the culture sheet. But the morphological change of the organization did not accept it.

Free Research Field

再生医療