Development of a method to improve QOL of elderly people by targeting new root caries bacterial species

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K20696
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Social dentistry
• Research Institution: Kagoshima University
• Principal Investigator: Obata Junko 鹿児島大学, 医歯学域歯学系, 助教 (70759448)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: P. acidifaciens / 根面う蝕 / 象牙質う蝕 / 高齢者

Outline of Final Research Achievements

Propionibacterium acidifaciens (P. acidifaciens) has newly been isolated from carious dentin lesions, but the cariogenicity of the organism remains unclear. The purpose of this study was to investigate the characteristics of the organism and their relationship to initiation of dentinal caries. P. acidifaciens was not aggregated with saliva. It had ability to adhere to hydroxyapatite beads. It had high ability to bind to collagen. It showed low resistance to hydrogen peroxide-producing bacteria. Biofilm formation was affected in acid environment. The results suggest the reasons for existence of the organism under the specific environment of carious dentin lesions.

Free Research Field

予防歯科学