2018 Fiscal Year Final Research Report
Early detection of arteriosclerosis for lower limbs: A novel measuring method of vascular endothelial function for lower limbs using oscillometric method
| Project/Area Number |
16K21076
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Intelligent mechanics/Mechanical systems
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Shizuoka University |
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Principal Investigator |
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| Research Collaborator |
Tsuji Toshio
Higashi Yukihito
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| Project Period (FY) |
2016-04-01 – 2019-03-31
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| Keywords | 動脈硬化 / 血管内皮機能 / Flow mediated dilation / ezFMD / オシロメトリック |
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| Outline of Final Research Achievements |
The purpose of this study is to produce of the simple measuring system of vascular endothelial function for lower limbs to detect initial arterioclerosis. We developed a novel measuring system of vascular endothelial function for lower limbs based on the oscillometric approach that measures cuff pressure and plethysmogram with a single air cuff. We demonstrated a measuring experiment of vascular endothelial function. The results indicated that the proposed system can estimate vascular endothelial function with high accuracy.
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| Free Research Field |
生体医工学
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| Academic Significance and Societal Importance of the Research Achievements |
下肢の血管内皮機能を非侵襲的に計測するシステムの開発は世界初の試みである．本システムが実用化されると，集団検診で下肢動脈硬化を早期発見できる可能性がある．また，動脈硬化から派生する疾患は非常に多く，本技術の実現によって動脈硬化を起因とする他の疾患に対しても予防する効果が期待できる．これは我が国全体の医療費削減の観点からも非常に重要な意義がある．
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