2017 Fiscal Year Final Research Report
Peri-implant bone loss initiated by titanium particle Osteolysis
| Project/Area Number |
16K21408
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dental engineering/Regenerative dentistry
Prosthodontics/ Dental materials science and
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| Research Institution | Nihon University |
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Principal Investigator |
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | インプラント周囲炎 |
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| Outline of Final Research Achievements |
Effects of titanium granules in the peri-implant bone loss was examined in the present research. First, we overviewed the current scientific knowledge and evaluated the quality of reports. As a result, there was no clinical evidence discussing the influence of titanium granules. In addition, it was shown that the quality of reporting by systematic review on peri-implant inflammation is low. Next, in the rat maxilla, titanium granules were scattered around the implant-abutment interface, and the change of the surrounding bone was analyzed assuming the same situation as the wear occurred. As a result, it was shown that the effect of titanium granules causes peri - implant bone resorption. Though we tried to analyze the mechanism using cultured cells, but we could not obtain the result indicating this.
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| Free Research Field |
歯科インプラント学
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