Cell growth in hypergravity using centrifugal microfluidic device and its application to cell culture systems

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K21493
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Nano/Microsystems; General pharmacology
• Research Institution: Osaka University
• Principal Investigator: Tonomura Wataru 大阪大学, 産業科学研究所, 特任助教(常勤) (50581493)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: マイクロ・ナノ流体デバイス / メカノバイオロジー

Outline of Final Research Achievements

Centrifugal microfluidic devices were developed in order to observe single-cell growth in environment of hypergravity. Qualitative analysis of microparticle behavior inside centrifugal microfluidic channels in environment of hypergravity, quantitative analysis of microparticle behavior inside centrifugal microfluidic channels in environment of hypergravity, and evaluation of deformability of single cell (blood cell) in centrifugal microfluidic channels, which was fabricated by softlithography technique using silicon rubber or nanoimprint technique using COP film, were observed.

Free Research Field

機械工学