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2017 Fiscal Year Final Research Report

Automated evaluation system of white matter hyper intensity and computer aided diagnosis for dementia using MRI

Research Project

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Project/Area Number 16K21660
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Medical systems
Research InstitutionTohoku University (2017)
National Center of Neurology and Psychiatry (2016)

Principal Investigator

Norihide Maikusa  東北大学, 東北メディカル・メガバンク機構, 助教 (80631069)

Project Period (FY) 2016-04-01 – 2018-03-31
KeywordsAlzheimer's disease / MRI
Outline of Final Research Achievements

We developed an automatic computer aided diagnostic method of Alzheimer's disease using longitudinal T1-MRI. This method used not only for atrophy of gray matter but also White matter hypo-intensity on T1 images.
To asses proposed method using data of Japanese Alzheimer's Disease Neuroimaging Initiative (J-ADNI).We used Support vector machine for Alzheimer group and healthy group using proposed method.As a result, it showed that it can be identified with a sensitivity of 87.9% and a specificity of 80.0%.

Free Research Field

医用画像解析

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Published: 2019-03-29  

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