2009 Fiscal Year Final Research Report
Development of Semiconductor PET Scanner with the Ultra High Resolutionof less than 1mm FWHM : Next Generation PET
| Project/Area Number |
17002010
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| Research Category |
Grant-in-Aid for Specially Promoted Research
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| Allocation Type | Single-year Grants |
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| Review Section |
Science and Engineering
Engineering
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| Research Institution | Tohoku University |
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Principal Investigator |
ISHII Keizo Tohoku University, 大学院・工学研究科, 教授 (00134065)
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| Co-Investigator(Kenkyū-buntansha) |
YAMAZAKI Hiromichi 東北大学, サイクロトロン・ラジオアイソトープセンター, 教授 (00166654)
MATSUYAMA Shigeo 東北大学, 大学院・工学研究科, 准教授 (70219525)
KIKUCHI Yohei 東北大学, 大学院・工学研究科, 助教 (50359535)
ITO Takashi 東北大学, 大学院・工学研究科, 教授 (20374952)
KOTANI Koji 東北大学, 大学院・工学研究科, 准教授 (20250699)
YANAI Kazuhiko 東北大学, 大学院・医学系研究科, 教授 (50192787)
HATAZAWA Jun 東北大学, 大学院・医学系研究科, 教授 (70198745)
ITO Nobuhiko 北里大学, 獣医畜産学部, 教授 (00159899)
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| Project Period (FY) |
2005 – 2009
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| Keywords | PET / 陽電子断層撮影装置 / 放射線 / システム工学 / 医療・福祉 |
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| Research Abstract |
The mortality rate for cancer is increasing every year and high resolution PETs which can detect minute cancer are called for now. We developed a semiconductor PET with a spatial resolution of less than 1mm by miniaturizing CdTe semiconductor detectors, while only about 4mm resolution is obtained in the conventional PET using scintillation detectors. It inspires the dawn of super-high resolution PET age. By a mouse experiment with the PET, we could show an FDG picture of 1mm cancers for the first time in the world. Furthermore, we succeeded to develop two-dimensional position sensitive CdTe detectors which provide both high resolution and high sensitivity. Stacking these detectors, we manufactured three-dimensional position sensitive detector blocks and developed a super-high resolution semiconductor PET for humans.
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[Journal Article] FDG imaging of 1mm tumor with an ultra high resolution animal PET2008
Author(s)
K. Ishii, Y. Funaki, Y. Kikuch, H. Yamazaki, S. Matsuyama, A. Terakawa, M. Fujiwara, R. Iwata, T. Kodama, Y. Watanabe, N. Tanizaki, D. Amano, T. Yamaguchi
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Journal Title
Proceeding of International Symposium on Biomedical Imaging
Pages: 1589-1592
Peer Reviewed
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[Journal Article] First achievement of less than 1mm FWHM resolution in practical semiconductor animal PET scanner2007
Author(s)
K. Ishii, Y. Kikuchi, S. Matsuyama, Y. Kanai, K. Kotani, T. Ito, H. Yamazaki, Y. Funaki, R. Iwata, M. Itoh, K. Yanai, J. Hatazawa, N. Itoh, et al., (他17名)
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Journal Title
Nuclear Instruments and Methods in Physics Research A576
Pages: 435-440
Peer Reviewed
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