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2009 Fiscal Year Final Research Report

Clinical application of genome-medical research

Research Project

  • PDF
Project/Area Number 17019025
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionShinshu University

Principal Investigator

FUKUSHIMA Yoshimitsu  Shinshu University, 医学部, 教授 (70273084)

Co-Investigator(Kenkyū-buntansha) SAKURAI Akihiro  信州大学, 医学部, 准教授 (70262706)
WAKUI Keiko  信州大学, 医学部, 助教 (50324249)
TAMAI Mariko  信州大学, 医学部, 准教授 (80283274)
MARUYAMA Eiji  神戸大学, 法学研究科, 教授 (10030636)
KOSUGI Shinji  京都大学, 医学研究科, 教授 (50252432)
NUMABE Hironao  京都大学, 医学研究科, 准教授 (00237801)
Project Period (FY) 2005 – 2009
Keywords遺伝学 / ゲノム / 遺伝カウンセリング / 生命倫理 / 社会医学
Research Abstract

The purpose of genome-medical research is development of diagnosis or treatment for various diseases. On the other hand, if the genomic information is inappropriately used, it would be harmful, because it is unchangeable and it embroils the relatives. We analyzed the three subjects in order to prepare for the new genomics era.
1. We proposed the new clinical system for clinical genetics on the basis of experiences in Shinshu University and Kyoto University.
2. We collected guidelines, law, or recommendations concerning with ELSI problems of genetic data or genome research, created database, and published on HP.
3. We proposed the methods for evaluation of clinical utility of genetic testing.

  • Research Products

    (6 results)

All 2007 2005 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Book (1 results) Remarks (1 results)

  • [Journal Article] A second generation human haplotype map of over 3. 1 million SNPs.2007

    • Author(s)
      The International HapMap Consortium (composed of 72 institutes, including Fukushima Y)
    • Journal Title

      Nature 449

      Pages: 851-861

    • Peer Reviewed
  • [Journal Article] The International HapMap Consortium, Community engagement and informed consent in the International HapMap project.2007

    • Author(s)
      Rotimi C, Leppert M, Fukushima Y, (他, 16名, 10番目)
    • Journal Title

      Community Genet. 10

      Pages: 186-98

    • Peer Reviewed
  • [Journal Article] A haplotype map of the human genome.2005

    • Author(s)
      The International HapMap Consortium (173 persons including Fukushima Y)
    • Journal Title

      Nature 437

      Pages: 1299-1320

    • Peer Reviewed
  • [Journal Article] Guidelines on Genetic Testing.2005

    • Author(s)
      Fukushima Y
    • Journal Title

      JMAJ (Japan Medical Association Journal) 48

      Pages: 429-431

    • Peer Reviewed
  • [Book] 遺伝医療と倫理・法・社会2007

    • Author(s)
      福嶋義光, 玉井真理子(編)
    • Total Pages
      1-215
    • Publisher
      メディカルドゥ
  • [Remarks] 「ゲノム医学研究成果の医療への応用に関する研究」班HP

    • URL

      http://gc.pbh.med.kyoto-u.ac.jp/g4c05/

URL: 

Published: 2011-06-18   Modified: 2012-08-15  

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