2009 Fiscal Year Final Research Report
Study of the microbial system based on high-throughput DNA sequencing
| Project/Area Number |
17020007
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| Research Category |
Grant-in-Aid for Scientific Research on Priority Areas
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| Allocation Type | Single-year Grants |
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| Review Section |
Biological Sciences
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| Research Institution | The University of Tokyo (2007-2009)
Kitasato University (2005-2006) |
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Principal Investigator |
HATTORI Masahira The University of Tokyo, 大学院・新領域創成科学研究科, 教授 (70175537)
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| Co-Investigator(Kenkyū-buntansha) |
YAMASHITA Atsushi 北里大学, 北里生命科学研究所, 助手 (20348585)
TOH Hidehiro 理化学研究所, 基幹研究所, 研究員 (10353468)
TAKAMI Hideto 海洋研究開発機構, 極限環境生物圏研究センター, グループリーダー (70359165)
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| Project Period (FY) |
2005 – 2009
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| Keywords | ゲノム / メタゲノム / 微生物 / 腸内細菌 |
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| Research Abstract |
In this study, we established a new research infrastructure for the analysis of the biological system of bacteria by using high-throughput DNA sequencing technologies. Particularly, we focused on the genome analysis of human microbes such as E. coli, Bifidobacteria and Lactobacillus species, and also established a culture-independent metagenomic approach by which the biological function of human gut microbiota was clarified by comprehensively identifying genes encoded by the gut microbiota including unculturable species.
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