Neural mechanism of visuo-motor control independent of self-induced sensory events

2009 Fiscal Year Final Research Report

• Project/Area Number: 17022019
• Research Category: Grant-in-Aid for Scientific Research on Priority Areas
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: Kyoto University
• Principal Investigator: KAWANO Kenji Kyoto University, 医学研究科, 教授 (40134530)
• Project Period (FY): 2005 – 2009
• Keywords: 運動制御 / 脳 / 視覚 / 選択 / 順応 / 眼球運動 / 受動的情報 / サル

Research Abstract

To investigate the neural mechanism that enables us to determine whether the image motion on the retina is genuine or self-induced, we recorded single neurons in the middle temporal (MT) and medial superior temporal (MST) areas in behaving monkeys. We found that MT neurons responded in relation to the retinal image motion, and MST neurons responded in relation to the genuine motion in the external world. The results suggest that MST neurons respond to visual motion in the external world while compensating the retinal image motion due to eye movements.

Research Products

• [Journal Article] Ocular responses to brief motion of textured backgrounds during smooth pursuit in humans (2009)
  • Author(s): Miura K, Kobayashi Y, Kawano K
  • Journal Title: J. Neurophysiol. 102 Pages: 1736-1747
  • Peer Reviewed
• [Journal Article] The effects of prolonged viewing of motion on short-latency ocular following responses (2009)
  • Author(s): Taki M, Miura K, Tabata H, Hisa Y, Kawano K
  • Journal Title: Exp Brain Res. 195 Pages: 195-205
  • Peer Reviewed
• [Journal Article] Relating neuronal firing patterns to functional differentiation of cerebral cortex (2009)
  • Author(s): Shinomoto S, Kim H, Shimokawa T, Matsuno N, Funahashi S, Shima K, Fujita I, Tamura H, Doi T, Kawano K, Inaba N, Fukushima K, Kurkin S, Kurata K, Taira M, Tsutsui K, Komatsu H, Ogawa T, Koida K, Tanji J, Toyama K
  • Journal Title: PLoS Computational Biology 5 Pages: 1000433
  • Peer Reviewed
• [Journal Article] MST neurons code for visual motion in space independent of pursuit eye movements. (2007)
  • Author(s): Inaba N, Shinomoto S, Yamane S, Takemura A, Kawano K
  • Journal Title: J. Neurophysiol. 97 Pages: 3473-83
  • Peer Reviewed
• [Journal Article] Deficits in short-latency tracking eye movements after chemical lesions in monkey cortical areas MT and MST. (2007)
  • Author(s): Takemura A, Murata Y, Kawano K, Miles FA
  • Journal Title: J. Neurosci. 27 Pages: 529-41
  • Peer Reviewed
• [Journal Article] Responses of MSTd and MT neurons during smooth pursuit exhibit similar temporal frequency dependence on retinal image motion.
  • Author(s): Inaba N, Kawano K
  • Journal Title: Cereb Cortex (in press)
  • Peer Reviewed
• [Presentation] Ocular following responses to moving color stimuli. (2009)
  • Author(s): Kawano K
  • Organizer: a Symposium in Honor of Fred Miles
  • Place of Presentation: Oxford, England
  • Year and Date: 2009-04-01
• [Presentation] irectional selectivity of MST neurons to background motion is preserved relative to the external world during smooth pursuit eye movements. (2008)
  • Author(s): Inaba N, Kawano K
  • Organizer: 38th Annual Meeting of the Society for Neuroscience
  • Place of Presentation: Washington D.C.
  • Year and Date: 2008-11-16
• [Presentation] The Visual Backup to the VOR: The Role of MT/MST. (2008)
  • Author(s): Kawano K, Takemura A.
  • Organizer: XXV Barany Society Meeting
  • Place of Presentation: Kyoto, Japan
  • Year and Date: 2008-04-02
• [Presentation] MST neurons are sensitive to visual motion in the external world during smooth pursuit. (2008)
  • Author(s): Kawano K.
  • Organizer: A Satellite Symposium to the XXV Barany Society Meeting
  • Place of Presentation: Ohtsu, Japan
  • Year and Date: 2008-03-31
• [Presentation] Neurons in areas MST/MT are sensitive to the temporal frequency of visual motion on the retina during smooth pursuit. (2007)
  • Author(s): Inaba N, Kawano K
  • Organizer: 37th Annual meeting of the Society for Neuroscience
  • Place of Presentation: San Diego, USA
  • Year and Date: 20071103-20071107