2009 Fiscal Year Final Research Report
Neuronal mechanisms of initiation and selection of adaptive locomotor behaviors
| Project/Area Number |
17075002
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research on Priority Areas
|
| Allocation Type | Single-year Grants |
|---|
| Review Section |
Science and Engineering
|
|---|
| Research Institution | Asahikawa Medical College |
|---|
Principal Investigator |
TAKAKUSAKI Kaoru Asahikawa Medical College, 医学部, 准教授 (10206732)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
MORI Futoshi 山口大学, 農学部, 准教授 (50301726)
YANAGIHARA Dai 東京大学, 大学院, 准教授 (90252725)
NAKAJIMA Katsumi 近畿大学, 医学部, 講師 (60270485)
INASE Masahiko 近畿大学, 医学部, 教授 (80249961)
YOSHIMI Kenji 順天堂大学, 医学部, 講師 (40450316)
NAKAZATO Taizo 順天堂大学, 医学部, 客員准教授 (80155697)
KITAZAWA Shigeru 順天堂大学, 医学部, 教授 (00251231)
OKUMURA Toshikatsu 旭川医科大学, 医学部, 教授 (60281903)
MATSUYAMA Kiyoji 札幌医科大学, 保健医療学部, 教授 (40209664)
KOYAMA Yoshimasa 福島大学, 理工学類, 教授 (80183812)
|
|---|
| Project Period (FY) |
2005 – 2009
|
| Keywords | 歩行 / 姿勢制御 / 情動 / 随意運動 / ドーパミン / 適応 / 自律神経系 |
|---|
| Research Abstract |
To initiate locomotion, predictive postural control based on cognitive information is essential. During ongoing locomotion, real-time postural control depending on sensory signals from mechanoreceptors is also required. In the present study, attempts have been made to examine integrate mechanisms of posture and locomotion in the various areas in the central nervous system using neurophysiological, neuropharmacological and molecular genetics assessments in various mammalian animal models. Our findings suggest that cortico-reticular and cortico-cerebellar systems are involved in the "predictive postural control", and a loop with cerebral cortex cerebellum and spinal cord including muscle tone control system may play major role in the "real-time postural control".
|
Research Products
(40 results)
-
-
[Journal Article] Dual involvement of G-substrate in motor learning revealed by gene deletion.2009
Author(s)
Endo S, Shutoh F, Dinh TL, Okamoto T, Ikeda T, Suzuki M, Kawahara SYanagihara D, Sato Y, Yamada K, Sakamoto T, Kirino Y, Hartell NA, Yamaguchi K, Itohara S, Nairn AC, Greengard P, Nagao S, Ito M.
-
Journal Title
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Journal Article] Input of orexin/hypocretin neurons revealed by genetically encoded tracer in mice.2005
Author(s)
Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama T, Shioda S, Yanagisawa M.
-
Journal Title
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
