2007 Fiscal Year Final Research Report Summary
Effect of weight-bearing after autologous osteochondral grafting surgery on stiffness parameter of articular cartilage of the osteochondral plug and range of knee motion
Project/Area Number |
17300185
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Rehabilitation science/Welfare engineering
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Research Institution | Kyoto University |
Principal Investigator |
KUROKI Hiroshi Kyoto University, Graduate School of Medicine, Professor (20170110)
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Co-Investigator(Kenkyū-buntansha) |
NAKAGAWA Yasuaki Kyoto University, Orthopaedic Surgery, Lecturer (90293860)
KOBAYASHI Masahiko Kyoto University, Orthopaedic Surgery, Assistant Professor (20378623)
SAKAKIMA Harutoshi Kagoshima University, Physical Therapy, Associate Professor (10325780)
OKA Toru Kyoto University, Physical Therapy, Research Student (20447923)
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Project Period (FY) |
2005 – 2007
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Keywords | Articular Cartilage / Autologous Osteochondral Transplantation / Ultrasound Stiffness Parameter / Weight Bearing / Range of Motion |
Research Abstract |
The osteochondral grafting surgery is often used for isolated cartilage lesions. Aim of this study was to investigate the effect of the surgery on articular cartilage of the osteochondral plug, bone healing and range of knee motion. Histology and ultrasound parameters of articular cartilage of the osteochondral plug were studied in the 6-mm model of rabbits. The rabbits were divided into two groups of the weight-bearing model and the non-weight-bearing model. The ultrasound stiffness parameter of articular 'cartilage of the plug decreased up to 12 weeks and then increased at 24 and 52 weeks after the surgery. Postoperative care for up to 12 weeks should be taken after the surgery. Part of this study has been publishedin 'Arthroscopy' and has been presented in the 2007 World Congress on Osteoarthritis.
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[Journal Article] Estimation of the mechanical property of meniscus using ultrasound: Examinations of native meniscus and effects of enzymatic digestion2007
Author(s)
Yasura K, Mizuno Y, Nakagawa Y, Mori K, Takenaka M, Ohashi T, Yamada K, Kobayashi M, Ando K, Kuroki H, Suzuki T, Ikeuchi K, Tsutsumi S, Nakamura T
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Journal Title
Journal of Orthopaedic Research 25
Pages: 884-893
Description
「研究成果報告書概要(和文)」より
Peer Reviewed
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[Journal Article] Sequential changes in implanted cartilage after autologous osteochondral transplantation : postoperative acoustic properties up to 1 year in an in vivo rabbit model2007
Author(s)
Hiroshi, Kuroki, Yasuaki, Nakagawa, Koji, Mori, Masahiko, Kobayashi, Yukihiro, Okamoto, Ko, Yasura, Kohei, Nishitani, Takashi, Nakamura
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Journal Title
Arthroscopy 23
Pages: 647-654
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Estimation of the mechanical property of nieniscus using ultrasound : Examinations of native meniscus and effects of enzymatic digestion2007
Author(s)
Ko, Yasura, Yasuyuki, Mizuno, Yasuaki, Nakagawa, Koji, Mori, Makoto, Takenaka, Tetsuo, Ohasbi, Keisuke, Yamada, Masahiko, Kobayashi, Keiji, Ando, Hiroshi, Kuroki, Takashi, Suzuki, Ken, Ikeuchi, Sadami, Tsutsumi, Takashi, Nakamura
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Journal Title
Journal of Orthopaedic Research 25
Pages: 884-893
Description
「研究成果報告書概要(欧文)」より
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[Presentation] Histological observations and ultrasound assessment of a fullthickness cartilage defect in 'a rabbit model2007
Author(s)
Hiroshi, Kuroki, Yasuaki, Nakagawa, Koji, Mori, Masahiko, Kobayashi, Yukihiro, Okamoto, Ko, Yasura, Kohei, Nishitani, Takashi, Nakamura
Organizer
The 2007 World Congress on Osteoarthritis
Place of Presentation
Warsaw, Poland
Year and Date
2007-09-29
Description
「研究成果報告書概要(欧文)」より
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