2007 Fiscal Year Final Research Report Summary
Investigation of Human Mechanism on Multimodal Perception/Memory andApplication to Early Diagnosis System for Dementia Disease
| Project/Area Number |
17360117
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Intelligent mechanics/Mechanical systems
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| Research Institution | Kagawa University |
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Principal Investigator |
TOUGE Tetsuo Kagawa University, Faculty of Medicine, Professor (80197839)
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| Co-Investigator(Kenkyū-buntansha) |
WU Jinglong Kagawa University, Faculty of Engineering, Professor (30294648)
KOCHIYAMA Takanori KAGAWA UNIVERSITY, ATR-Promotions, Brain Activity imaging Center, 研究員 (90380146)
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| Project Period (FY) |
2005 – 2007
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| Keywords | Mechanical Engineering / Intelligent Machine / Mechanical Systems / Human Machine Systems |
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| Research Abstract |
In order to investigate human mechanism on multimodal perception/memory and application to early diagnosis system for dementia disease, we have measured human characteristics on visual, auditory and tactile perception and attention, memory and language higher functions by behavior, EEG and fMRI experiments. The important results can summary as follows.
The visual behavior experimental results may suggested that the visual circular vection (CV) to be more compelling when the spatial frequency from 0.053cycle/deg to 0.084 cycle/deg and high luminance of visual stimuli in central vision field. We developed the wide-view visual presentation system with a horizontal visual angle of 120 deg and a vertical angle of 120 deg using nonmagnetic optical fibers and contact lens for fMRI. In this paper, we introduce the functions and performance of this system and report the results of our evaluative experiment.
Auditory experimental results suggested that the effect of the earplug on sound localizati
… More
on ability had two causes, sound insulation and spectral change.
We developed a novel automatic tactile pattern delivery system that is capable of perform the tactile cognitive and neuroimaging procedures. The results indicated that the performance of active and passive touch depend on the similar rate of the tactile patterns. Human raised angle discrimination was increased as the standard angular was increased when the standard angular was smaller than 90°. The raised angle discrimination ability was at a same level, when the standard angular was larger than 90°.
The brain-imaging data showed a partial overlap between visual spatial attention and auditory spatial attention. In addition, it revealed a partial overlap between the neural systems involved in the performance of visual spatial attention versus visual temporal attention. Function segregation in the left inferior frontal gyrus was investigated in an fMRI experiment using a passive listening task, in which Japanese subjects were required to passively listen to words and nonsense words in Japanese and English.
The above basic research results providing basic dada to develop the early diagnosis system for dementia disease. Less
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[Journal Article] The validity of a hyperventilation test for an investigation of autonomic failure: assessment in patients with multiple system atrophy and Parkinson's disease2006
Author(s)
Deguchi K, Sasaki I, Ikeda K, Shimamura M, Urai Y, Tsukaguchi M, Urai Y, Tsukaguchi M, Touge T, Takeuchi H, Kuriyama S.
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Journal Title
Int J Clin Pract 2006Dec;60(12)
Pages: 1542-1547
Description
「研究成果報告書概要(和文)」より
Peer Reviewed
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[Journal Article] Unilateral ibotenic acid lesions of the prefrontal cortex reduce rotational behavior in 8-hydroxydopamine-lesioned rats2006
Author(s)
Gonzalez, D., Miyamoto, 0., Touge, T., Sumitani, K., Kuriyama, S., Itano, T
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Journal Title
Acta med Okayama, 2006Dec 60(6)
Pages: 319-324
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] The validity of a hyperventilation test for an investigation of autonomic failure : assessment in patints with multiple system atrophy and Parkinson's disease2006
Author(s)
Deguchi, K., Sasaki, I., Ikeda, K., Shimamura, M., Urai, Y., Tsukaguchi, M., Touge, T., Takeuchi, H., Kurayama, S
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Journal Title
Int J clin pract 60(12)
Pages: 1542-1547
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Changes of parvalbumin immunoreactive neurons and GFAP immunoreactive astrocytes in the rat lateral geniculate nucleus following monocular enucleation2006
Author(s)
Gonzalez, D., Satriotomo, I., Miki, T., Lee, KY., Yokoyama, T., Touge, T., Matsumoto, Y., Li, HP., Kuriyama, S., Takeuchi, Y
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Journal Title
Neurosci Lett, 2006Mar6 395(2)
Pages: 149-154
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] 手指触覚による長さ認知特性に関する考察-fMRIによる人間高次脳機能の計測2005
Author(s)
呂 勝富, 酒井 義郎, 呉 景龍, 北沢 雅之, 小笠原 淳一, 山内 秀一, 山本 正幸, 葛 盛, 根 来清, 松永 尚文
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Journal Title
システム制御情報学会論文誌 Vol.18,No.4
Pages: 136-145
Description
「研究成果報告書概要(和文)」より
Peer Reviewed
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[Journal Article] Study about the cognitive characteristic of Length by the finger tactile sense-Measurement on human advanced function of brain by fMRI2005
Author(s)
S. Lu, Y. Sakayi, J. Wu, M. Kitazawa, J. Ogasawara, S. Yamauchi, M. Yamamoto, S. Ge, K. Negoro, N. Matsunaga
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Journal Title
Transactions of the Institute of Systems, control and information engineers Vol.18 No.4
Pages: 136-145
Description
「研究成果報告書概要(欧文)」より
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[Presentation] Attention systems and neural responses to visual and auditory stimuli : an ±MRI study2007
Author(s)
Chunlin, Li, Takanori, Kochiyama, Jinglong, Wu, Dehua, Chui, Takaaki, Tsuge, Kunihiko, Osaka
Organizer
IEEE/ICME International Conference on Complex Medical Engineering
Place of Presentation
Beijing China
Year and Date
20070500
Description
「研究成果報告書概要(欧文)」より
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[Presentation] Web Intelligence Meets Immunology2005
Author(s)
Jiming Liu, Ning Zhong, Yiyu Yao and Jing-long Wu
Organizer
The First International Conference on Complex Medical Engineering-CEE2005
Place of Presentation
香川県
Year and Date
20050500
Description
「研究成果報告書概要(和文)」より
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[Presentation] Web Intelligence Meets Immunology2005
Author(s)
Jiming, Liu, Ning, Zhong, Yiyu, Yao, Jing-long, Wu
Organizer
The First International Conference on Complex Medical Engineering-CME2005
Place of Presentation
Kagawa, Japan
Year and Date
20050500
Description
「研究成果報告書概要(欧文)」より
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[Presentation] A Functional Magnetic Resonance Imaging Study of the Retinotopic Organization of the Peripheral Visual Field in the Human Visual Cortex2005
Author(s)
Zhen, Zhang, Takanori, Kochiyama, Kunihilo, Osaka, Keita, Moriwaki, Jinwu, Qian, Jing-long, Wu
Organizer
The 2005 International Conference on Active Media Technology
Place of Presentation
Kagawa, Japan
Year and Date
20050500
Description
「研究成果報告書概要(欧文)」より
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