2006 Fiscal Year Final Research Report Summary
Anti-stress effects of green odor emanating from forest
| Project/Area Number |
17500467
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | University of Toyama |
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Principal Investigator |
SASAKI Kazuo University of Toyama, Grad. Sch. of Sci and Eng., Prof. (60042826)
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| Co-Investigator(Kenkyū-buntansha) |
ISOBE Masaharu University of Toyama, Grad. Sch. of Sci and Eng., Prof. (70211050)
NAKAJIMA Kazuki University of Toyama, Grad. Sch. Of Sci and Eng., Assoc. Prof. (50207776)
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| Project Period (FY) |
2005 – 2006
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| Keywords | stress / forest-bathing / green odor / cedrol / lateral hypothalamic area / serntonin / dopamine |
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| Research Abstract |
1. The paraventricular nucleus of the thalamus (PVNT) is a relay nucleus from the midbrain and hypothalamus to the cerebral cortex, and a important brain site for formation of behavior. Fos expression in the PVNT increased after forced swimming in rats, but it significantly decreased in rats exposed to green odor, an odorant emanating from green leaves.
2. There was no significant difference in extracellular 5-HT levels in the lateral hypothalamic area (LHA) after immobilization stress between green odor-exposed and-non-exposed rats. However, 5-HIAA levels in the LHA augmented after immobilization stress in green odor-non-exposed rats was significantly decreased in green odor-exposed rats.
3. Cedrol is an odorant emanating from the trunk of trees. Levels of dopamine and its metabolites increased after immobilization stress in rats, but their levels were significantly decreased in cedrol-exposed rats.
4. These results suggest that odorants emanating from trees have anti-stress effects through a mechanism which decreases 5-HT and/or dopamine release in the LHA.
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[Journal Article] Leptin facilitates learning and memory performance and enhances hippocampal Cal long-term potentiation and CaMX II phosphorylation in rats.2006
Author(s)
Oomura Y, Hori N, Shiraishi T, Fukunaga K, Takeda H, Tsuji M, Matsumiya T, Ishibashi M, Aou 5, Li XL, Kohno D, Uramura K, Sougawa H, Yada T, Wayner MJ, Sasaki K
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Journal Title
Peptides 27
Pages: 2738-2749
Description
「研究成果報告書概要(欧文)」より
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