2006 Fiscal Year Final Research Report Summary
Solid State Asymmetric Synthesis using A New Chiral Porous Metal-Organic Frame Work
| Project/Area Number |
17550109
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Kansai University |
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Principal Investigator |
TANAKA Koichi Kansai Univ., Faculty of Enginnering., Prof., 工学部, 教授 (10116949)
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| Project Period (FY) |
2005 – 2006
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| Keywords | Porous Metal-Organic Frame Work / Chirality / Solid State Reaction / Asymmetric Reaction / Solvent-free Reaction / Cyclohexenoxide / Aniline / Crystal Structure |
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| Research Abstract |
A new porous chiral metal-organic framework (2) has been synthesized by treating axially chiral 2,2'-dihydroxy-1,1'-binaphthyl-5,5'-dicarboxylic acid (1) with Cu salts and its crystal structure has been elucidated by X-ray analysis. The porous chiral metal-organic framework (2) includes two MeOH molecules in the square cavity (15Åx15Å) constructed by coordination of 1 with Cu atom.
In the presence of the porous chiral metal-organic framework (2), enantioselective addition reaction of aniline to 1,2-epoxycyclohexane (3) proceeded in 51% ee to give an optically active aminolacohol (4) at room temperature. This is the first example for such a enantioselective reaction in chiral porous metal-organic framework.
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[Book] 無溶媒有機合成2005
Author(s)
田中 耕一
Total Pages
71
Publisher
関西大学 工学会
Description
「研究成果報告書概要(和文)」より
