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2007 Fiscal Year Final Research Report Summary

Coupling Problem of Solid-Liquid System of Biological Tissue Adaptive Distributed Processing of FEM

Research Project

Project/Area Number 17560064
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Materials/Mechanics of materials
Research InstitutionTokyo University of Agriculture and Technology

Principal Investigator

SAKUMA Atsushi  Tokyo University of Agriculture and Technology, Institute of Symbiotic Science and Technology, Associate Professor (60274180)

Project Period (FY) 2005 – 2007
KeywordsBiological Tissue / Viscoelasticity / Medical Examination. / Medical Engineering / Simulation / FEM / Deformation Analysis / Control
Research Abstract

Biological tissue consists of cells and their deformation affects to various mechanics in medical and biotechnological field.
A bi-axial tensile testing machine is developed to control the amount of tensile displacement by using servo motor in the first step of this research. Then the testing machine is used under birefringent microscope for the observation of strain distribution in the tissue. The results of the testing indicate that the inside of cells is filled by structural materials and the structure causes the difficulties in the analysis of the tissue deformation.
The complicated deformation of the tissue is also observed in macroscopic testing systems. Fundamental tensile testing is adopted to evaluate the viscoelastic behavior of the tissue which is affected by the solid-liquid coupled structure. The constitutive model of 3-element solid is used in the evaluation and it indicates that the tissue have high nonlinearity even if industrial materials like metal have low one.
The nonlinearity caused by the cellar structure is also observed in other macroscopic testings. Uniaxial and biaxial testings are adopted to the observation, and the representation idea of the nonlinearity is shown by using transformation theory.
And then the adaptive distribution techniques of FEM are discussed for the research objective. The adaptation of FE domain is realized by using the equation of load balance. Continuous analysis between different materials is realized by modification of solving procedure.
As the conclusion of this research, some study on nonlinearity of the cellar structure and viscous deformation is evaluated with the development of testing machines. The adaptation method of distributed FEM is also discussed for the research objectives.

  • Research Products

    (38 results)

All 2008 2007 2006 2005

All Journal Article (12 results) (of which Peer Reviewed: 6 results) Presentation (26 results)

  • [Journal Article] 低密度多孔質材の負荷経路依存性評価のための等2軸予ひずみ条件における圧縮試験2008

    • Author(s)
      佐久間淳, 他3名
    • Journal Title

      日本機械学会論文集 (掲載決定)(CD-ROM)

      Pages: 6pages

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Atsushi, SAKUMA, Naoto, AZUSAWA, Masamitsu, SHINOMIYA, Shigeru NAGAKI2008

    • Author(s)
      Atsushi, SAKUMA, Naoto, AZUSAWA, Masamitsu, SHINOMIYA, Shigeru NAGAKI
    • Journal Title

      Journal of Japan Society of Mechanical Engineers (in Print)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Study on Nonlinear Deformation of High-porosity Porous Materials using Constitutive Equation incorporating Phase Transformation2007

    • Author(s)
      Atsushi SAKUMA, 他2名
    • Journal Title

      9th International Conference on Computational Plasticity(COMPLAS 2007) 9

      Pages: 366-369

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Application of Constitutive Equation incorporating Phase Transformation to Compressive Deformation of Low-density Porous Materials2007

    • Author(s)
      Atsushi SAKUMA, 他2名
    • Journal Title

      3rd Asian-Pacific Congress on Computational Mechanics(APCOM 2007) 9

      Pages: 366-369

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Study on Nonlinear Deformation of High-porosity Porous Materials using Constitutive Equation incorporating Phase Transformation2007

    • Author(s)
      Atsushi, SAKUMA, Naoto, AZUSAWA, Shigeru, NAGAKI
    • Journal Title

      9th International Conference on Computational Plasticity (COMPLAS 2007)

      Pages: 366-369

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Application of Constitutive Equation incorporating Phase Transformation to Compressive Deformation of Low-density Porous Materials2007

    • Author(s)
      Atsushi, SAKUMA, Naoto, AZUSAWA, Shigeru, NAGAKI
    • Journal Title

      3rd Asian-Pacific Congress on Computational Mechanics (APCOM 2007) (CD-ROM)

      Pages: 6

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] 細胞集合組織の巨視的変形過程におけるひずみ複屈折の顕微鏡観察2006

    • Author(s)
      佐久間淳, 他3名
    • Journal Title

      日本機械学会論文集 70-2

      Pages: 169-275

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Valuation of Nonlinear Three-Element-Solid Constitutive Equation for Biomechanical Simulation2006

    • Author(s)
      Atsushi SAKUMA, 他4名
    • Journal Title

      2nd Asia-Pacific International Conference on Numerical Method in Engineering(ICOME 2006) 2(CD-ROM)

      Pages: 6pages

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Analysis of Bending and Stretching of Human Body using Biomechanical Simulation2006

    • Author(s)
      Atsushi SAKUMA, 他4名
    • Journal Title

      2nd Asia-Pacific International Conference on Numerical Method in Engineering(ICOME 2006) 2(CD-ROM)

      Pages: 6pages

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Microscopic Observation of Strain-Induced Birefrigence on Macroscopic Deformation Process of Biological Tissue2006

    • Author(s)
      Mizue, EBISAWA, Atsushi, SAKUMA, Yukitoshi, OTANI
    • Journal Title

      Journal of Japan Society of Mechanical Engineers 72-724

      Pages: 2079-2085

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Valuation of Nonlinear Three-Element-Solid Constitutive Equation for Biomechanical Simulation2006

    • Author(s)
      Mitsuhiro, TANI, Atsushi, SAKUMA, Makoto, OGASAWARA, Tsukasa, TADOMI, Eiichi, YANAGISAWA
    • Journal Title

      Proceedings of 2nd Asia-Pacific International Conference on Numerical Method in Engineering 6(CD-ROM)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Analysis of Bending and Stretching of Human Body using Biomechanical Simulation2006

    • Author(s)
      Naoki, USHIMURA, Atsushi, SAKUMA, Makoto, OGASAWARA, Tsukasa, TADOMI, Eiichi, YANAGISAWA
    • Journal Title

      Proceedings of 2nd Asia-Pacific International Conference on Numerical Method in Engineering 6(CD-ROM)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] 直立姿勢制御における主動筋と拮抗筋の機能に関するロボティクス2008

    • Author(s)
      佐久間淳, 他3名
    • Organizer
      日本機械学会第20回 バイオエンジニアリング講演会
    • Place of Presentation
      東京都
    • Year and Date
      2008-01-25
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 3要素固体モデルの非線形物性値の同定法とその生体軟組織への適用2008

    • Author(s)
      佐久間淳, 他4名
    • Organizer
      日本機械学会第20回 バイオエンジニアリング講演会
    • Place of Presentation
      東京都
    • Year and Date
      2008-01-25
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 生体軟組織のin vivo粘弾性特性同定を目的とした押込試験法の検討2008

    • Author(s)
      佐久間淳, 他2名
    • Organizer
      日本機械学会第20回 バイオエンジニアリング講演会
    • Place of Presentation
      東京都
    • Year and Date
      2008-01-25
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 軟組織の粘弾性変形の圧力依存性計測のための擬似生体環境槽の開発2008

    • Author(s)
      佐久間淳, 他5名
    • Organizer
      日本機械学会第20回 バイオエンジニアリング講演会
    • Place of Presentation
      東京都
    • Year and Date
      2008-01-25
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Robotics on Role of Agonist and Antagonist in Control of Upright Standing2008

    • Author(s)
      Atsushi SAKUMA, et. al.
    • Organizer
      Preprint of the Japan Society of Mechanical Engineers
    • Place of Presentation
      Tokyo
    • Year and Date
      2008-01-25
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Valuation Technique of Nonlinear Parameters in Three Element Solid Model and Its Application to Biological Soft Tissue2008

    • Author(s)
      Atsushi SAKUMA, et. al.
    • Organizer
      Preprint of the Japan Society of Mechanical Engineers
    • Place of Presentation
      Tokyo
    • Year and Date
      2008-01-25
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Valuation of Indentation Testing for in vivo Measurement of Viscoelasticity in Biological Soft Tissue2008

    • Author(s)
      Atsushi SAKUMA, et. al.
    • Organizer
      Preprint of the Japan Society of Mechanical Engineers
    • Place of Presentation
      Tokyo
    • Year and Date
      2008-01-25
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Development of Virtual in vivo Vessel for Measurement of Pressure Dependence of Viscoelastic Deformation in Biological Soft Tissue2008

    • Author(s)
      Atsushi SAKUMA, et. al.
    • Organizer
      Preprint of the Japan Society of Mechanical Engineers
    • Place of Presentation
      Tokyo
    • Year and Date
      2008-01-25
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Evaluation of Compression Process of Low-density Porous Materials using Constitutive Relationship incorporating Phase Transformation2007

    • Author(s)
      Atsushi SAKUMA, et. al.
    • Organizer
      Preprint of Society of Materials Science, Japan
    • Place of Presentation
      Kyoto-city
    • Year and Date
      2007-11-29
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] 低密度多孔質材の圧縮変形挙動の相変態を考慮した構成モデルによる検討2007

    • Author(s)
      佐久間淳, 他3名
    • Organizer
      第51回日本学術会議材料工学連合講演会
    • Place of Presentation
      京都市
    • Year and Date
      2007-11-27
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 低密度多孔質材の圧縮変形のひずみ速度依存性の相変態を考慮した構成式による評価2007

    • Author(s)
      佐久間淳, 他4名
    • Organizer
      日本機械学会 第20回計算力学講演会
    • Place of Presentation
      京田辺市
    • Year and Date
      2007-11-26
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Evaluation of Strain-rate Dependency of Low-density Porous Material in Compression Process by Constitutive Equation incorporating Phase Transformation2007

    • Author(s)
      Atsushi SAKUMA, et. al.
    • Organizer
      Preprint of the Japan Society of Mechanical Engineers
    • Place of Presentation
      Kyotanabe-city
    • Year and Date
      2007-11-26
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] 多体系連成問題における接触メカニズムの数値解析モデル2006

    • Author(s)
      佐久間淳, 他1名
    • Organizer
      日本機械学会講演論文集第19回計算力学講演会
    • Place of Presentation
      名古屋市
    • Year and Date
      2006-11-03
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Numerical Modeling of Contact Mechanism for Analysis of Multibody Coupled Problem2006

    • Author(s)
      Atsushi SAKUMA, et. al.
    • Organizer
      Preprint of the Japan Society of Mechanical Engineers
    • Place of Presentation
      Nagoya-city
    • Year and Date
      2006-11-03
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Reliability of Parameter Valuation in Nonlinear Three-element Solid Model2006

    • Author(s)
      Atsushi SAKUMA, et. al.
    • Organizer
      Preprint of Society of Materials Science, Japan
    • Place of Presentation
      Nagaoka-city
    • Year and Date
      2006-05-27
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] 3要素固体モデルにおける非線形物性値同定の信頼性評価2006

    • Author(s)
      佐久間淳, 他2名
    • Organizer
      日本材料学会学術講演会
    • Place of Presentation
      長岡市
    • Year and Date
      2006-05-22
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 軟組織の圧力条件を考慮した粘弾性変形同定のための引張試験法,日本機械学会講演論文集2006

    • Author(s)
      佐久間淳, 他2名
    • Organizer
      日本機械学会第18回バイオエンジニアリング講演会
    • Place of Presentation
      新潟市
    • Year and Date
      2006-01-13
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 押込試験による生体軟組織の変形特性計測のためのシステム構成2006

    • Author(s)
      佐久間淳, 他2名
    • Organizer
      日本機械学会第18回バイオエンジニアリング講演会
    • Place of Presentation
      新潟市
    • Year and Date
      2006-01-13
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 筋の粘弾性特性を考慮した胴体部の屈伸運動解析2006

    • Author(s)
      佐久間淳, 他2名
    • Organizer
      日本機械学会第18回バイオエンジニアリング講演会
    • Place of Presentation
      新潟市
    • Year and Date
      2006-01-13
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Tensile Testing for Valuation of Visco Elastic Deformation in Soft Tissue under Pressure Condition2006

    • Author(s)
      Atsushi SAKUMA, et. al.
    • Organizer
      Preprint of the Japan Society of Mechanical Engineers
    • Place of Presentation
      Niigata-city
    • Year and Date
      2006-01-13
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] System Development of Compression Testing for Valuation of in vivo Soft Tissue2006

    • Author(s)
      Atsushi SAKUMA, et. al.
    • Organizer
      Preprint of the Japan Society of Mechanical Engineers
    • Place of Presentation
      Niigata-city
    • Year and Date
      2006-01-13
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Analysis of Bending and Stretching of Human Body considering Visco Elasticity of Muscles2006

    • Author(s)
      Atsushi SAKUMA, et. al.
    • Organizer
      Preprint of the Japan Society of Mechanical Engineers
    • Place of Presentation
      Niigata-city
    • Year and Date
      2006-01-13
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] ゼラチンの2軸応力下における複屈折による挙動観察,日本機械学会講演論文集2005

    • Author(s)
      佐久間淳, 他2名
    • Organizer
      日本機械学会講演論文集第18回計算力学講演会
    • Place of Presentation
      つくば市
    • Year and Date
      2005-11-19
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] FEMの領域分割法における適応負荷分散法に関する考察2005

    • Author(s)
      佐久間淳, 他1名
    • Organizer
      日本機械学会講演論文集第18回計算力学講演会
    • Place of Presentation
      つくば市
    • Year and Date
      2005-11-19
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Observation of Gelatin Under Stress Condition by Birefrigence2005

    • Author(s)
      Atsushi SAKUMA, et. al.
    • Organizer
      Preprint of the Japan Society of Mechanical Engineers
    • Place of Presentation
      Tsukuba-city
    • Year and Date
      2005-11-19
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] A Study on the Adaptive Load Distribution of FEM Using Decomposition Method2005

    • Author(s)
      Atsushi SAKUMA, et. al.
    • Organizer
      Preprint of the Japan Society of Mechanical Engineers
    • Place of Presentation
      Tsukuba-city
    • Year and Date
      2005-11-19
    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2010-02-04  

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