2006 Fiscal Year Final Research Report Summary

Immobilization of Photoelectric Dye on the Polyethylene Film Surface -A Prototype Retinal Prosthesis-

Research Project

Project/Area Number	17560605
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Composite materials/Physical properties
Research Institution	Okayama University
Principal Investigator	UCHIDA Tetsuya Graduate School of Natural Science and Technology, Assistant, 大学院自然科学研究科, 助手 (90284083)
Co-Investigator(Kenkyū-buntansha)	SHIMAMURA Kaoru Graduate School of Natural Science and Technology, Professor, 大学院自然科学研究科, 教授 (80013506) MATSUO Toshihiko Graduate School of Medicine and Dentistry, Associate Professor, 大学院医歯薬学総合研究科, 助教授 (90211565)
Project Period (FY)	2005 – 2006
Keywords	Photoelectric Dye / Retinal Prosthesis / Polyethylene / Film / Surface
Research Abstract	Polyethylene (PE) film was treated with fuming nitric acid at 80°C for 20 min, resulting in introduction of COOH moieties on the film surface. The COOH's were reacted with ethylenediamine, whose amino groups were used for linking with (2-[4-(dibutylamino)phenyl]ethenyl)-3-carboxy-methylbenzo-thiazolium, photoelectric dye (NK-5962), which absorbs visible light and converts the photon energy to electric potentials. The dye molecules were immobilized on the PE film surface and they were able to stimulate chick retinal tissues on incidence of visible light. These facts hopefully lead to development of an artificial retinal prosthesis.

(3 results)