2006 Fiscal Year Final Research Report Summary
Immunoglobulin genes of teleosts : Discovery of new immunoglobulin class.
| Project/Area Number |
17580164
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General fisheries
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| Research Institution | University of Miyazaki |
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Principal Investigator |
SAKAI Masahiro University of Miyazaki, Faculty of Agriculture, Professor, 農学部, 教授 (20178536)
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| Project Period (FY) |
2005 – 2006
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| Keywords | immunoglobulin / carp / fugu / IgT / teleost |
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| Research Abstract |
Characterization of teleost IGH loci is near completion. Although. the basic structure of the IGH loci is conserved, species specific variations exist across teleosts. In general, teleosts have three major Ig heavy chain isotypes. Analysis of IGH genomic region suggests no additional discovery of IgH genes will be forthcoming, at least not from downstream region of d gene (Bengten et al. 2006). The novel Ig isotype along with IgM and IgD will be good tools to study the immune responses and biology of 3-cells in fish.
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