2007 Fiscal Year Final Research Report Summary
The development of the simple DNA typing using SNP of the mitochondrial and Y chromosomal DNA from the old sample
Project/Area Number |
17590572
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Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Legal medicine
|
Research Institution | Yamagata University |
Principal Investigator |
UMETSU Kazuo Yamagata University, Legal Medicine, Associate Professor (10091828)
|
Co-Investigator(Kenkyū-buntansha) |
YUASA Isao Tottori University, Legal Medicine, Associate Professor (00093633)
|
Project Period (FY) |
2005 – 2007
|
Keywords | mitochondoria DNA / Y-SNP / haplogroup / DNA polymorphism / denatured sample / 遺伝子頻度 |
Research Abstract |
Analyzing system by the APLP (amplified product-length polymorphism) method of haplogroups which could correspond to mitochondrial and Y chromosomal DNA was developed. 45 SNP on mitochondrial DNA and 24 SNP on Y chromosomal DNA were selected, and haplogroup was judged by the APLP method. This method was sufficiently applicable for degraded samples which decreased very much in molecular weight, because these methods had done DNA under 150 bp to the target. These haplotypes are fairly continent and/or region-specific, therefore, we can infer the ethnic background of that DNA.
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Research Products
(2 results)