2006 Fiscal Year Final Research Report Summary
Effects of prolonged exposure on brain activation of a PTSD patients using script driven fMRI
| Project/Area Number |
17591239
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | National Center of Neurology and Psychiatry |
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Principal Investigator |
KIM Yoshiharu National Center of Neurology and Psychiatry, Division of Adult Mental Health, Director, 精神保健研究所 成人精神保健部, 部長 (60225117)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAJIMA Satomi National Center of Neurologyand Psychiatry, Division of Adult Mental Health, section chief, 室長 (20285753)
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| Project Period (FY) |
2005 – 2006
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| Keywords | PTSD / CBT / fMRI |
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| Research Abstract |
We tried to detect the change in brain function in PTSD will to compare the findings pre-and post-treatment in same Individual. Here, the above mentioned effect of secondary reaction to trauma will be canceled by having the difference of the brain image findings at two time periods, which is the aim of this study, the detail of which will be presented elsewhere. The shift of the activate are between pre-and post-treatment, from the area of visual cognition to the Broca's area, corresponds to the change in the clinical profile. The client first said that she felt as if she were overwhelmed by the vivid imagery of the rape, being hardly unable to talk about it, while after the treatment she became capable of talking about the experience without being captivated by the imagery. The possibilities are 1) this reflects the recovery of the PTSD, 2) the gaining of new coping, namely, verbal reasoning skill, 3) individual traits of how to react to the trauma and gain resilience, or 4) the nature of the treatment, for the PE encourages the client to talk on the trauma. To answer these question, further studies should be needed. Being aware of these, the authors find it very likely that the cortical involvement, especially verbal reorganization plays a crucial role in the recovery process of PTSD.
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