2006 Fiscal Year Final Research Report Summary
Study of Blue Cone under Pathological Conditions in Rabbit Eyes
| Project/Area Number |
17591821
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Chiba University |
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Principal Investigator |
YAMAMOTO Shuichi Chiba University, Graduate School of Medicine, Professor, 大学院医学研究院, 教授 (20230550)
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| Co-Investigator(Kenkyū-buntansha) |
YOTSUKURA Jiro Chiba University, Hospital, Assistant Professor, 医学部附属病院, 講師 (00240367)
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| Project Period (FY) |
2005 – 2006
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| Keywords | Electroretinogram / Blue cone / LED built-in contact lens electrode / Retinal degeneration / Rabbit eye |
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| Research Abstract |
1) To examine the blue cone electroretinogram, we developed the blue LED built-in contact lens electrode.
2) Responses from the blue cone were clearly and repeatedly recorded from normal human eyes using this new electrode.
3) Temporal frequency characteristics obtained from the electroretinogram was quite similar those reported in previous psychophysical studies.
4) Smaller contact lenses were developed for rabbit eyes, and the blue cone electroretinograms were successfully recorded.
5) Electroretinograms were examined in patients with various retinal diseases, and in several animal models.
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[Journal Article] Up-regulation of genes for oxidative phosphorylation and protein turnover in diabetic mouse retina.2006
Author(s)
Adachi-Uehara N, Kato M, Nimura Y, Seki N, Ishihara A, Matsumoto E, Iwase K, Ohtsuka S, Kodama H, Mizota A, Yamamoto S, Adachi-Usami E, Takiguchi M.
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Journal Title
Exp Eye Res. 83
Pages: 849-857
Description
「研究成果報告書概要(欧文)」より
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