2007 Fiscal Year Final Research Report Summary
Effects of zinc deficiency on the transduction of taste sensation
| Project/Area Number |
17591919
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Kyushu Dental College |
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Principal Investigator |
TOYOSHIMA Kuniaki Kyushu Dental College, School of Dentisry, Professor (10112559)
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| Co-Investigator(Kenkyū-buntansha) |
SETA Yuji Kyushu Dental College, School of Dentisry, Associate Professor (90291616)
TOYONO Takashi Kyushu Dental College, School of Dentisry, Assistant Professor (10311929)
KATAOKA Sinji Kyushu Dental College, School of Dentisry, Assistant Professor (80364149)
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| Project Period (FY) |
2005 – 2007
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| Keywords | taste bud / taste transduction / zinc / transcription / promoter / umami / sweet / taste sensation |
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| Research Abstract |
Taste disorders have been linked to zinc deficiency. Zinc plays structural roles in so called Zinc fingers. Zinc fingers are exploited by transcription factors for interacting with DNA and regulating the activity of genes. Although the mechanisms of transcriptional regulation of the taste receptor genes have not been revealed, it is possible that the zinc is concerned with the transcriptional regulation of taste receptor genes. Therefore, we examined the molecular mechanisms regulating the promoter of human umami and sweet receptor, T1R3 gene in a human intrahepatic bile duct carcinoma cell line, H_uCCT1. The luciferase reporter assay showed that the 226-bp region upstream of the ATG had promoter activity.
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Author(s)
Takata Y, Ansai T, Soh I, Kimura Y, Yoshitake Y, Sonoki K, Awano S, Kagiyama S, Yoshida A, Nakamichi I, Hamasaki T, Torisu T, Toyoshima K, Takehara T
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Journal Title
Description
「研究成果報告書概要(和文)」より
Peer Reviewed
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[Journal Article] Physical fitness and cognitive function in an 85-year-old community-dwelling population2008
Author(s)
Takata Y, Ansai T, Soh I, Kimura Y, Yoshitake Y, Sonoki K, Awano S, Kagiyama S, Yoshida A, Nakamichi I, Hamasaki T, Torisu T, Toyoshima K, Takehara, T
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Journal Title
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] 高齢者における血清レプチンと味覚感度との関連について2007
Author(s)
安細 敏弘, 瀬田 祐司, 豊野 孝, 園木 一男, 吉田 明弘, 粟野 秀慈, 邵 仁浩, 濱崎 朋子, 高田 豊, 竹原 直道, 豊島 邦昭
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Journal Title
日本味と匂学会誌 14(3)
Pages: 599-600
Description
「研究成果報告書概要(和文)」より
Peer Reviewed
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[Journal Article] S.Kataoka, R.Yang, Y.Ishimaru, H.Matsunami, J.Sevigny, JC.Kinnamon,and TE.Finger;The Candidate Sour Taste Receptor,PKD2L1, Is Expressed by Type III Taste Cells in the Mouse2007
Author(s)
S.Kataoka, R.Yang, Y.Ishimaru, H.Matsunami, J.Sdvigny, JC.Kinnamon, and TE.Finger
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Journal Title
Chemical Senses 33(3)
Pages: 243-253
Description
「研究成果報告書概要(和文)」より
Peer Reviewed
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[Journal Article] 九州歯科大学歯学部学生の講義および実習の達成度および満足度に関するアンケート調査2007
Author(s)
豊野, 孝, 高田, 豊, 荒井, 秋晴, 稲永, 清敏, 後藤, 哲哉, 西原, 達次
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Journal Title
日本歯科医学教育学会雑誌 23(3)
Pages: 341-349
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] 高齢者における血清レプチンと味覚感度との関連について2007
Author(s)
安細, 敏弘, 瀬田, 祐司, 豊野, 孝, 園木, 一男, 吉田, 明弘, 粟野, 秀慈, 郡, 仁浩, 濱崎, 朋子, 高田, 豊, 竹原, 直道, 豊島, 邦昭
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Journal Title
日本味と匂い学会誌 14(3)
Pages: 599-600
Description
「研究成果報告書概要(欧文)」より
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[Presentation] 高齢者における血清レプチンと味覚感度との関連について2007
Author(s)
安細 敏弘, 瀬田 祐司, 豊野 孝, 園木 一男, 吉田 明弘, 粟野 秀慈, 邵 仁浩, 濱崎 朋子, 高田 豊, 竹原 直道, 豊島 邦昭
Organizer
2007年度日本味と匂学会第41回記念大会
Place of Presentation
タワーホール船堀(東京)
Year and Date
20070726-28
Description
「研究成果報告書概要(和文)」より
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[Presentation] 高齢者における血清レプチンと味覚感度との関連について2007
Author(s)
安細, 敏弘, 瀬田, 祐司, 豊野, 孝, 園木, 一男, 吉田, 明弘, 粟野, 秀慈, 郡, 仁浩, 濱崎, 朋子, 高田, 豊, 竹原, 直道, 豊島, 邦昭
Organizer
2007年度目本味と匂学会第41回記念大会
Place of Presentation
タワーホール船堀(東京)
Year and Date
20070726-28
Description
「研究成果報告書概要(欧文)」より
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[Presentation] 味蕾細胞の分化におけるMash1の役割2007
Author(s)
瀬田, 祐司, 片岡, 真司, 豊野, 孝, 豊島, 邦昭
Organizer
第112回日本解剖学会総会・全国学術集会
Place of Presentation
大阪国際会議場
Year and Date
20070327-29
Description
「研究成果報告書概要(欧文)」より
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[Presentation] Promoter analysis of human umami receptor, T1R1 gene2007
Author(s)
Toyono, T., Seta, Y., Kataoka, S., Toyoshima, K
Organizer
The 5th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception
Place of Presentation
Nishijin Plaza,Kyushu University,Fukuoka
Year and Date
2007-11-02
Description
「研究成果報告書概要(和文)」より
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[Presentation] Promoter analysis of human umami receptor, T1R1 gene2007
Author(s)
Toyono, T., Seta, Y., Kataoka, S., Toyoshima, K
Organizer
The 5th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception
Place of Presentation
Nishijin Plaza, Kyushu University, Fukuoka
Year and Date
2007-11-02
Description
「研究成果報告書概要(欧文)」より
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[Presentation] ラット味蕾におけるP2×4の発現2006
Author(s)
瀬田, 祐司, 片岡, 真司, 豊野, 孝, 豊島, 邦昭
Organizer
平成18年度日本味と匂学会第40回記念大会
Place of Presentation
九州大学医学部百年講堂
Year and Date
20060711-13
Description
「研究成果報告書概要(欧文)」より
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[Presentation] 医歯薬出版2006
Author(s)
豊島, 邦昭, 他
Organizer
口腔組織・発生学
Place of Presentation
共著
Year and Date
20060000
Description
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[Presentation] 医歯薬出版2006
Author(s)
豊島, 邦昭, 他
Organizer
第6版TenCate 口腔組織学
Place of Presentation
共訳
Year and Date
20060000
Description
「研究成果報告書概要(欧文)」より
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[Presentation] 味蕾におけるATP受容体の発現2005
Author(s)
片岡 真司、豊野 孝、瀬田 祐司、豊島 邦昭
Organizer
日本顕微鏡学会第50回シンポジウム
Place of Presentation
福岡
Year and Date
20051101-02
Description
「研究成果報告書概要(和文)」より
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