Development of made to order image diagnostic system for cervical metastaic lymph nodes in patients with oral cancer.

2007 Fiscal Year Final Research Report Summary

• Project/Area Number: 17591979
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Pathobiological dentistry/Dental radiology
• Research Institution: Fukuoka Dental College
• Principal Investigator: YUASA Kenji Fukuoka Dental College, Faculty of Dentistry, Professor (40136510)
• Co-Investigator(Kenkyū-buntansha): KAGAWA Toyohiro Fukuoka Dental College, Faculty of Dentistry, Assistant Professor (00258592) ; OZEKI Satoru Fukuoka Dental College, Faculty of Dentistry, Professor (80117077) ; TANIGUCHI Kunihisa Fukuoka Dental College, Faculty of Dentistry, Professor (90105685) ; MIWA Kunihiro Fukuoka Dental College, Faculty of Dentistry, Assistant Professor (10136509) ; OGAWA Kazuhisa Fukuoka Dental college, Faculty of Dentistry, Lecture (90105726)
• Project Period (FY): 2005 – 2007
• Keywords: Oral cancer / Cervical lymph node / Ultrasonography / CT / MRI

Research Abstract

Results of this rematch is as fellows; 1) Detection ration of swelling cervical lymph nodes using STIR of MR imaging was equal to that of CT 2) Detection ration of swelling cervical lymph ncdes using Diffusion weighted whole body imaging with background signal suppression (DWIBS) was superior to that of CT. However, DWIBS was not useful for diagnosing metastasis. 3) Probability of metastasis was 70.2%in case of diagnosing as metastasis, 4.1% in case of diagnosing as “Perhaps, it was not metastasis. However, observation was necessary “and 4.1% in case of diagnosing as reactive swelling lymph node, using ultrasonography. 4) Very hyperintensity or hyperintensity area in T2 weighted image (T2WI) of MR imaging suggested cystic degeneration or keratinization in pathological fmdings. It was considered that these fmdings of T2WI were specific for matastatic lymph nodes. Tumor cells and fibrous tissue were not presented specific fmdings on MR images. It was considered that differentiation between tumor cell and normal lymphoid tissue was difficult. 5) Small ROI method of dynamic MRI, which was developed by us, was more useful for detecting tumor cells in lymph node than conventional ROI method. 6) It was considered that low attention area on CT images suggested fat tissue, hemorrhage, hyperemia or follicular hyperplasia. 7) I was suggested that vascular ration of lymph nodes on Doppler ultrasonograms depended on inflammation of teeth and jaw bones. 8) We developed imaging reporting system for cervical lymph node, which send to about200PCs through LAN of our hospital information system.