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2006 Fiscal Year Final Research Report Summary

Evaluation of metastatic lymph node of oral cancer using dynamic MRI

Research Project

Project/Area Number 17592080
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Surgical dentistry
Research InstitutionOkayama University

Principal Investigator

KONOUCHI Hironobu  OKAYAMA University, ORAL RADIOLOGY, Senior Assistant Professor, 医学部・歯学部附属病院, 講師 (20294423)

Co-Investigator(Kenkyū-buntansha) ASAUMI Jun-ichi  OKAYAMA University, ORAL RADIOLOGY, Senior Assistant Professor, 医学部・歯学部附属病院, 講師 (60184131)
YANAGI Yosinobu  OKAYAMA University, ORAL RADIOLOGY, Assistant, 医学部・歯学部附属病院, 助手 (50284071)
KONNDOU Seiji  SHIMANE University, ORAL SURGERY, Assistant, 医学部, 助手 (10432634)
Project Period (FY) 2005 – 2006
Keywordscancer / dynamic MRI / oral S.C.C. / metastatic LN / metastatic factor / MRI
Research Abstract

Object: The presence of regional metastatic lymph nodes in patients with oral cancer alter the treatment and the
prognosis. Ultrasound, CT and MRI are useful tools for diagnosing of regional metastatic lymph nodes which is evaluated by morphological factors such as the shape, size and numbers. The accuracy of morphological factors is high but incomplete. The enhanced pattern of dynamic MRI correlated with intratumor angiogenesis, which corresponds closely to tumor growth. To provide additional information for diagnosis of regional lymph nodes, we investigated the relationship between the enhanced patterns acquired by dynamic MRI of metastatic lymph nodes and that of non-metastatic lymph nodes in oral squamous cell carcinoma (SCC). Methods: Twenty patients with primary oral SCC underwent dynamic MRI using three dimensional fast imaging with steady-state precession (FISP) sequence. The enhanced pattern of dynamic MRI of regional lymph nodes and morphological findings were acquired. The relationship between the enhanced pattern and morphological findings was analyzed. In the same patients, the relationship between the enhanced pattern of metastatic lymph nodes and non-metastatic lymph nodes was also analyzed. Results: Regarding the diagnosis for metastatic lymph nodes, morphological findings were more accurate than the enhanced pattern of dynamic MRI. There was no correlation between morphological findings and enhanced pattern of dynamic MRI. In the same patients, the metastatic lymph nodes were showed similar enhanced pattern to the primary site. On the other hand the enhanced pattern of non-metastatic lymph nodes was not similar to that of metastatic lymph and/or that of primary site. Conclusion: Dynamic MRI appeared to improve the evaluation of regional metastatic lymph nodes.

  • Research Products

    (6 results)

All 2007 2006

All Journal Article (6 results)

  • [Journal Article] Diagnostic value of dynamic contrast-enhanced MRI in the salivary gland tumors.2007

    • Author(s)
      久富 美紀
    • Journal Title

      Oral Oncology (In press)

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Diagnostic value of dynamic contrast-enhanced MRI in the salivary gland tumors.2007

    • Author(s)
      MIKI HISATOMI
    • Journal Title

      Oral Oncology (In press)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Enhancement effects of test injection with a small amount of MR contrast medium in the oral and maxillofacial region2006

    • Author(s)
      柳 文修
    • Journal Title

      Eur J Radiol. Sep;59(3)

      Pages: 367-370

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Usefulness of contrast enhanced-MRI in the diagnosis of unicystic ameloblastoma.2006

    • Author(s)
      此内 浩信
    • Journal Title

      Oral Oncology May;42(5)

      Pages: 481-486

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Enhancement effects of test injection with a small amount of MR contrast medium in the oral and maxillofacial region.2006

    • Author(s)
      YOSHINOBU YANAGI
    • Journal Title

      Eur J Radiol. Sep;59(3)

      Pages: 367-70

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Usefulness of contrast enhanced-MRI in the diagnosis of unicystic ameloblastoma.2006

    • Author(s)
      HIRONOBU KONOUCHI
    • Journal Title

      Oral Oncology May;42(5)

      Pages: 481-6

    • Description
      「研究成果報告書概要(欧文)」より

URL: 

Published: 2008-05-27  

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