The research on maintenance of intestinal function and role of commensal bacteria by physical stress such as exercise under heat / hypoxic environment

2021 Fiscal Year Final Research Report

• Project/Area Number: 17H02147
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Sports science
• Research Institution: Kawasaki University of Medical Welfare
• Principal Investigator: Matsuo Kaori 川崎医療福祉大学, 医療技術学部, 准教授 (60513570)
• Co-Investigator(Kenkyū-buntansha): 後藤 一成 立命館大学, スポーツ健康科学部, 教授 (60508258) ; 岡崎 和伸 大阪市立大学, 都市健康・スポーツ研究センター, 教授 (70447754)
• Project Period (FY): 2017-04-01 – 2022-03-31
• Keywords: 腸内細菌叢 / 腸内環境 / 暑熱環境 / 低酸素環境 / トレーニング / コンディショニング

Outline of Final Research Achievements

Clarifying the interaction between exercise and internal organs contributes to the improvement of performance or the maintenance of health. This study focused on intestinal dysfunction caused by various stresses such as changes in the outside environment and investigated the role of the gut microbiota in the deterioration of intestinal symptoms.
There was no change in the classification of gut microbiota in the untrained group in animal studies. However, the gut microbiota showed changes in the training group. It was suggested that resistance training or endurance training utilizing a hypoxic exposure is less effective for muscle hypertrophy. However, the visceral fat weight was significantly decreased in the hypoxic group.
In addition, in the intervention study for athletes, changes in the stool shape were shown due to training in a heat environment. These results suggested that it may be used as a basic material for athletes training in heat environments.

Free Research Field

スポーツ免疫学　トレーニング科学　環境生理学

Academic Significance and Societal Importance of the Research Achievements

本研究の学術的意義は、外部環境変化など種々のストレスが原因となり引き起こされる腸管機能障害に注目し、腸内環境の悪化に腸内細菌叢がどのような役割を担うかを調べ、対処策・予防策を見出すことである。
アスリートの暑熱・低酸素環境での運動・トレーニングが身体に及ぼす影響に焦点を絞り、動物実験研究とヒト対象試験によって、腸内環境維持のメカニズムの一部を明らかにした。
本研究の成果は、外部環境変化に対応した腸内環境維持のコンディション対策やアスリートの腸内環境を考慮したトレーニング処方への還元が期待できる。さらに、一般成人の生活習慣病予防の運動処方や健康維持・増進への貢献に繋がる社会的意義が高いと考えられる。