Study on preventive method of development and/or rupture of abdominal aortic aneurysm

2020 Fiscal Year Final Research Report

• Project/Area Number: 17H03822
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Food science
• Research Institution: Kindai University
• Principal Investigator: zaima nobuhiro 近畿大学, 農学部, 准教授 (40455572)
• Co-Investigator(Kenkyū-buntansha): 佐々木 健 浜松医科大学, 医学部, 技術専門員 (20397433) ; 田中 宏樹 浜松医科大学, 医学部, 特任研究員 (50456563)
• Project Period (FY): 2017-04-01 – 2021-03-31
• Keywords: 腹部大動脈瘤 / 血管

Outline of Final Research Achievements

Abdominal aortic aneurysm is a vascular disease with silent graduation of abdominal aorta. Several previous studies suggested that dietary habits affect the development of abdominal aortic aneurysm. However, the relationship between dietary habits and abdominal aortic aneurysm are clearly unknown. In this study, we found several food factors which have pro-aneurysm and anti-aneurysm effect. In addition, we reported mechanisms of action of the food factors. These findings provide important basic evidence to develop method of preventing abdominal aortic aneurysm.

Free Research Field

食品科学

Academic Significance and Societal Importance of the Research Achievements

これまで不明な点が多かった腹部大動脈瘤の進展と食生活の関係を明らかにするために必要な基礎研究基盤を構築した。構築した基礎研究基盤から、腹部大動脈瘤の進展を抑制する可能性のある成分や促進する可能性のある成分などが明らかになった。これらの研究は、腹部大動脈瘤の破裂を食品成分で予防するための方法の確立に貢献できると期待される。